In 2018, Revive & Restore hosted this press event in Cape May, New Jersey, a location renowned for its concentrations of shorebirds and breeding horseshoe crabs. The event was joined by the state’s First Lady Tammy Murphy, the New Jersey Audubon Society, and representatives of Eli Lilly to announce research findings that were soon to be published in PLOS Biology. This page presents that event and those findings.
2018 press event
TURNING THE TIDE FOR HORSESHOE CRABS:
NEW HOPE FOR AN ANCIENT SPECIES
New Study Proves Synthetic Can Replace Horseshoe Crab Blood in Biomedical Testing
Revive & Restore’s Press Conference | May 10, 2018 | Cape May, New Jersey
Revive & Restore’s review paper Saving the Horseshoe Crab: A Synthetic Alternative to Horseshoe Crab Blood for Endotoxin Detection found:
- The synthetic alternative to the current standard endotoxin test, Recombinant Factor C (rFC), is just as efficacious, safe, and reliable as the product made from the blood of horseshoe crabs.
- rFC causes fewer false positives than the product made from the blood of horseshoe crabs and is cost-effective.
- rFC is becoming more widely available since patent protections have expired.
- The use of rFC for testing in the manufacturing process of injectable medications is allowed under U.S. Food & Drug Administration guidelines
- Using rFC in pharmaceutical manufacturing process could reduce the need to use horseshoe crab blood by 90 percent.
In the Press
- “Alternative to horseshoe crab blood for medical testing may save species,” The Press of Atlantic City | May 12, 2018
- “Inside the Biomedical Revolution to Save Horseshoe Crabs and the Shorebirds That Need Them, ” Audubon Magazine | May 11, 2018
- “The Last Days of the Blue-Blood Harvest,” The Atlantic | May 9, 2018
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