Sex-ratio-biasing constructs for the control of invasive lower vertebrates

By February 11, 2015Workgroup 3

Author(s): Thresher, et al.

Publication: Nature Biotechnology

Publication Date: Date 2014

Abstract: There are few cost-effective means of controlling the many types of invasive fish, amphibians and reptiles that cause substantial economic and ecological damage worldwide. Notable examples include sea lampreys (Petromyzon marinus), common carp (Cyprinus carpio), cane toads (Bufomarinus), bullfrogs (Rana catesbeiana) and the brown tree snake (Boiga irregularis)1. Genetic strategies based on constructs that heritably reduce female survival or fertility2–4 could provide a solution…

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