New Genomic Solutions for
Conservation Problems Workshop
April 6-9, 2015 – Sausalito, California
MONDAY, APRIL 6, 2015
4:00 pm — Hotel check-in begins
5:00 pm — Reception & Introductions
Meet the participants, work group leaders and workshop organizers
6:30 pm — Evening buffet dinner
TUESDAY, APRIL 7, 2015
MORNING
7:30-8:30 — Breakfast
8:30-9:00 — Welcome, review of agenda, goals and outcomes
Ryan Phelan, Stewart Brand, and Kent Redford
PLENARY SESSIONS
9:00-10:15 — WHAT CONSERVATION WANTS
Host: Kent Redford — Introduction / Overview
Bringing the group to a common understanding of conservation practice, its history and desired outcomes and provide four brief examples of successful practice.
Examples of Success—
Innovative models of genomic technology applications to conservation problems
Panelists: Luke Alphey (mosquitoes), Bill Powell (chestnut tree), Josh Donlan (island restoration),
Oliver Ryder (California condors)
10:15-10:30 — Break
10:30-11:30 — WHAT GENOMICS CAN DO
Host: Stewart Brand — Introduction
Bringing the group to a common understanding of the state of current genomic technology, providing a brief description of a variety of tools that might be applied to help deliver desired conservation outcomes.
Panelists: George Church (CRISPR), Kevin Esvelt (Gene Drive), Fred Gould (RNAi),
Ronald Thresher (Engineered Sterility)
11:30-12:00 — Introduction of the 3 Work Groups
Review of deliverables for Version 1.0
Host: Ryan Phelan
Work groups leaders: #1 Margaret Wild, #2 Billy Karesh, #3 Josh Donlan
AFTERNOON
12:00-12:30 — Break, grab lunch, and take to work group breakout rooms
DEVELOPING VERSION 1.0
12:30 – 3:30 — WORK GROUP SESSION: Developing Version 1.0
Work groups leaders: #1 Margaret Wild, #2 Billy Karesh, #3 Josh Donlan
In each work group:
A few invited panelists will present case studies that highlight in some depth the problem facing the candidate species, the host, the vector, and the current treatment approaches;
The group will then explore potential ways that new technologies might be applied to address the specific threats to the species.
Prepare for plenary session a 20-minute presentation (slides optional) reviewing your group’s case studies, sharing what were the most difficult issues addressed, and the potential intervention points for genomic technologies that have the greatest promise. (This will be referred to as Version 1.0.)
3:30-4:00 – Break
PLENARY SESSION
4:00-6:00 — PRESENTATIONS & DISCUSSION (reviewing Version 1.0)
Each work group presents for 20 min their Version 1.0 followed by 20 min of open discussion
Host: Kent Redford
This plenary will provide an opportunity for all participants to hear from each of the work groups and to get up to speed on the problems and solutions that they are working on—especially any interesting realizations that have emerged from their first breakout session.
Plenary will also provide an opportunity for the work groups to get feedback from all participants that can help shape their thinking going forward and further refine their approach.
6:00-7:00 — Break (outside, weather permitting)
7:00 — Buffet Dinner
WEDNESDAY, APRIL 8, 2015
MORNING
7:30-8:15 — Breakfast
MORNING PLENARY SESSION
8:15-9:00 — REVIEW OF DAY ONE
Host: Kent Redford
Comments, suggestions and open discussion
9:00– 10:00 — ETHICAL, LEGAL, REGULATORY CONSIDERATIONS
Host: Stewart Brand
Panelists: Gregg Howald, Jennifer Kuzma, and Eleanor Pauwels
This morning we will make the transition from technical, biological considerations to those that will influence the feasibility of implementation and begin to think about those social, cultural and regulatory factors that might limit each groups’ proposed genomic interventions. These considerations should influence our thinking before we fully design Version 2.0
10:00-10:15 — Break
10:15-1:30 —WORK GROUP SESSION: Developing Version 2.0 (includes a working lunch).
Work groups leaders: #1 Margaret Wild, #2 Billy Karesh, #3 Josh Donlan
– Discuss the social, political and regulatory challenges that would face implementation of the interventions you are suggesting.
– Prioritize those challenges that might be most difficult to overcome and brainstorm ways to address these—we refer to this as creating your Version 2.0 approach.
– Prepare 20-minute presentation to share your new insights in plenary session.
1:30-1:45 — Break
1:45-3:15 — PLENARY SESSION (Reviewing Version 2.0)
Host: Ryan Phelan
This plenary will provide an opportunity for all participants to hear about each work group’s Version 2.0 and to provide an opportunity for the work groups to get feedback from all participants.
3:00 — Review Guidelines for Funding “Pitch”
3:15-3:45 — Break
3:45-5:30 — FINAL BREAKOUT INTO WORKING GROUPS (Developing Version 3.0)
Work groups leaders: #1 Margaret Wild, #2 Billy Karesh, #3 Josh Donlan
Tomorrow each work group will have a total of 15 minutes “to pitch” your best idea to our “Funding Strategy Panel” and to your colleagues. For each intervention proposed by your group, prepare a compelling business case (identifying the problem, the proposed solution, the value proposition and strategic opportunities). Additional guidelines will be provided on site.
5:30-6:00 — Break
6:00 — Wine reception
6:30 —Buffet Dinner
7:15 — After-dinner presentation
Host: Alexander Rose, The Long Now Foundation
David Lang, Co-founder of OpenROV —“Makers & Science”
THURSDAY MORNING, APRIL 9, 2015
Location: Surfbird
7:30-8:30 — Breakfast
PLENARY SESSION
8:30-9:00 — BRINGING THE FUNDING PERSPECTIVE INTO THE EQUATION:
Viewpoints from business, philanthropy and government
Host: Ryan Phelan
Panelists: Bob Cook, Drew Endy, Alicia Jackson, Ed Schulak
9:00-11:00
– Presentation of one final project from each group (15 minutes each)
– Candid reactions and suggestions from biotech investors and other stakeholders on the funding potential for the projects to be presented
– Candid reactions and suggestions from other participants
11:00-11:15 — Break
11:15-12:00 — NEXT STEPS
Host: Kent Redford
Wrap up and outcomes—what should be done next and by whom? Closing reflections by a few participants. Excitement about moving forward!
12:00 —Lunch
Departures
(Advisory Committee meets)